S-Adenosyl methionine (SAM-e)
Meropenem is an intravenous β-lactam antibiotic used to treat a variety of bacterial infections. Some of these include meningitis, intra-abdominal infection, pneumonia, sepsis, and anthrax. Meropenem usually results in bacterial death by blocking their ability to make a cell wall. It is more resistant to breakdown by β-lactamase producing bacteria.
| CAS | 29908-03-0 |
|---|---|
| FORMULA | C15H22N6O5S |
| MIN ORDER QUANTITY (MOQ) | |
| PHARMACOPOEIA | BP/USP |
| APPEARANCE | |
| Melting point | 326.8 °C (620.2 °F) |
Description
S-Adenosyl methionine (SAM-e) is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throughout the body, most SAM-e is produced and consumed in the liver. More than 40 methyl transfers from SAM-e are known, to various substrates such as nucleic acids, proteins, lipids, and secondary metabolites. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase.
In bacteria, SAM-e is bound by the SAM riboswitch, which regulates genes involved in methionine or cysteine biosynthesis. In eukaryotic cells, SAM-e serves as a regulator of a variety of processes including DNA, tRNA, and rRNA methylation immune response amino acid metabolism transsulfuration, and more. In plants, SAM-e is crucial to the biosynthesis of ethylene, an important plant hormone, and signaling molecule.
Additional information
| CAS | 29908-03-0 |
|---|---|
| FORMULA | C15H22N6O5S |
| PHARMACOPOEIA | BP/USP |
| Melting point | 326.8 °C (620.2 °F) |
